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Commentary Vav-1 and T cells

✍ Scribed by Doreen Cantrell

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
53 KB
Volume
33
Category
Article
ISSN
0014-2980

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Several findings support the importance of GM1-enriched lipid microdomains of plasma membrane and of Vav, an essential regulator of actin cytoskeletal rearrangement, in the regulation of T cell activation. Moreover, a functional link among lipid microdomains, Vav and the HIV product Nef has been des