✦ LIBER ✦

Combining dependent P-values

✍ Scribed by James T Kost; Michael P McDermott

Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 121 KB
Volume: 60
Category: Article
ISSN: 0167-7152
DOI: 10.1016/s0167-7152(02)00310-3

No coin nor oath required. For personal study only.

✦ Synopsis

We derive an approximation to the null distribution of Fisher's statistic for combining p-values when the underlying test statistics are jointly distributed as multivariate t with common denominator. Applications to testing problems involving order-restricted parameters are brie y discussed.

📜 SIMILAR VOLUMES

On Fisher's Method of Combining p-Values

✍ R. C. Elston 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 345 KB

Truncated product method for combining P

Truncated product method for combining P-values

✍ D.V. Zaykin; Lev A. Zhivotovsky; P.H. Westfall; B.S. Weir 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 122 KB

We present a new procedure for combining P-values from a set of L hypothesis tests. Our procedure is to take the product of only those P-values less than some specified cut-off value and to evaluate the probability of such a product, or a smaller value, under the overall hypothesis that all L hypoth

Pathway analysis by adaptive combination

Pathway analysis by adaptive combination of P-values

✍ Kai Yu; Qizhai Li; Andrew W. Bergen; Ruth M. Pfeiffer; Philip S. Rosenberg; Neil 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 139 KB

## Abstract It is increasingly recognized that pathway analyses—a joint test of association between the outcome and a group of single nucleotide polymorphisms (SNPs) within a biological pathway—could potentially complement single‐SNP analysis and provide additional insights for the genetic architec

Approximations to a conservative inverse

Approximations to a conservative inverse chi-square procedure for combining p-values in integrative research

✍ Hilary Saner 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 676 KB

Serial P-values

✍ M. Aickin 📂 Article 📅 1983 🏛 Elsevier Science 🌐 English ⚖ 845 KB

Bayes p-values

✍ Peter Thompson 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 306 KB

The form of a Bayes p-value is given when the loss function in a testing problem with a point null is an increasing function of the p-value. A complete class result and an essentially complete class result are given.