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Combined use of rapamycin and leflunomide in prevention of acute cardiac allografts rejection in rats

✍ Scribed by Sun, Yan; Chen, Xi; Zhao, Jiabin; Zou, Xiaoming; Li, Gang; Li, Xiaolin; Shen, Bin; Sun, Shibo

Book ID
119382978
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
679 KB
Volume
27
Category
Article
ISSN
0966-3274

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The effect of rapamycin (RAPA) and cyclosporine A (CsA) monotherapy and combination therapy was examined in prevention of kidney allograft rejection in the mouse. Both drugs were administered orally for up to 14 days in BALB/c (H-2 d ) to C57BL/6 (H-2 b ) mice strong combination. Six groups were tre