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Combined treatment with PTH (1–34) and OPG increases bone volume and uniformity of mineralization in aged ovariectomized rats

✍ Scribed by A. Valenta; P. Roschger; N. Fratzl-Zelman; P.J. Kostenuik; C.R. Dunstan; P. Fratzl; K. Klaushofer


Book ID
116319165
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
367 KB
Volume
37
Category
Article
ISSN
8756-3282

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To evaluate the potential use of a combination of parathyroid hormone (PTH) and estrogen as therapy for osteoporosis, we examined the effects of combined and separate administration of low-dose PTH and estradiol in ovariectomized rats with established osteopenia. Ovariectomized rats were untreated f