Combined multidrug chemotherapy (vincristine, bleomycin, and methotrexate) and radiotherapy in advanced carcinomas of the head and neck: Results of a pilot study of the radiation therapy oncology group
β Scribed by Victor A. Marcial; Nayda R. Figueroa; Enrique Velez-Garcia; Juan Cintron; Luis A. Vallecillo
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 160 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0360-3016
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A combination of cisplatin, methotrexate, bleomycin, and vincristine (CABO) was assessed in advanced epidermoid head and neck cancer. Among 72 patients with recurrent or metastatic disease and measurable lesions, there were 9 complete and 27 partial responses for an overall response rate of 50%. The
## For the EORTC Head and Neck Cooperative Group A total of 185 eligible patients with advanced inoperable squamous cell carcinoma of the head and neck were randomized into two groups; the cisplatin, methotrexate, bleomycin, and vincristine (CABO) group received cisplatin (50 mg/m2; day 4), methot
## Abstract Fortyβthree patients with Stage III or IV squamous cell carcinoma of the head and neck were treated with simultaneous hydroxyurea and bleomycin in four treatment levels and with fullβdose radiotherapy. Complete responses ranged from 28 to 50% (P = .47), and complete plus partial respons