## Abstract The sites of deposition of atherosclerotic plaque on the aortic wall are considered to be influenced by secondary and retrograde flow patterns that cause regions of altered shear stress. To detect secondary flow patterns and areas of retrograde flow in the abdominal aorta, velocity‐enco
Combined MR imaging and CFD simulation of flow in the human descending aorta
✍ Scribed by Nigel B. Wood; Simon J. Weston; Philip J. Kilner; A. David Gosman; David N. Firmin
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 511 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1053-1807
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✦ Synopsis
Abstract
A combined MR and computational fluid dynamics (CFD) study is made of flow in the upper descending thoracic aorta. The aim was to investigate further the potential of CFD simulations linked to in vivo MRI scans. The three‐dimensional (3D) geometrical images of the aorta and the 3D time‐resolved velocity images at the entry to the domain studied were used as boundary conditions for the CFD simulations of the flow. Despite some measurement uncertainties, comparisons between simulated and measured flow structures at the exit from the domain demonstrated encouraging levels of agreement. Moreover, the CFD simulation allowed the flow structure throughout the domain to be examined in more detail, in particular the flow separation region in the distal aortic arch and its influence on the downstream flow during late systole. Additional information such as relative pressure and wall shear stress, which could not be measured via MRI, were also extracted from the simulation. The results have encouraged further applications of the methods described. J. Magn. Reson. Imaging 2001;13:699–713. © 2001 Wiley‐Liss, Inc.
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