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Combined liquid chromatography-mass spectrometry for trace analysis of pharmaceuticals

✍ Scribed by Lothar Schmidt; Harald Danigel; Hartmut Jungclas


Publisher
Elsevier Science
Year
1982
Weight
203 KB
Volume
198
Category
Article
ISSN
0167-5087

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## Abstract LC‐ESI‐MS is applied frequently in pharmaceutical analysis. The sample amount is generally not restricted, however with LC‐ESI‐MS, a lack of sensitivity may still be observed with standard‐bore LC columns in isocratic mode. Therefore, it was investigated whether increased sensitivity co