Reversal of drug resistance mediated by
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Zhe-Sheng Chen; Shunji Aoki; Masaharu Komatsu; Kazumitsu Ueda; Tomoyuki Sumizawa
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Article
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2001
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John Wiley and Sons
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French
β 140 KB
π 1 views
## We previously isolated agosterol A (AG -A) from a marine Spongia sp. and found that it completely reversed colchicine resistance in P-glycoprotein (Pgp)-over-expressing KB-C2 cells and vincristine resistance in multidrug-resistance protein (MRP)1-over-expressing CV60 cells. However, a tri-deacet