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Combined effect of gefitinib ('Iressa', ZD1839) and targeted radiotherapy with211At-EGF

✍ Scribed by ÅsaLiljegren Sundberg; Ylva Almqvist; Anna Orlova; Erik Blomquist; HolgerJ. Jensen; Lars Gedda; Vladimir Tolmachev; Jörgen Carlsson

Book ID: 105962007
Publisher: Springer
Year: 2003
Tongue: English
Weight: 403 KB
Volume: 30
Category: Article
ISSN: 0340-6997
DOI: 10.1007/s00259-003-1308-9

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## Abstract Some kinds of breast cancer cell lines, similar to several types of solid tumors, express epidermal growth factor receptor (EGFR). However, gefitinib, an EGFR tyrosine kinase inhibitor, is not effective for all these cell lines. Similarly, taxane is effective for many of the cell lines,