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The effect of gefitinib (Iressa, ZD1839) in combination with oxaliplatin is schedule-dependent in colon cancer cell lines

✍ Scribed by Jian-Ming Xu; Amalia Azzariti; Giuseppe Colucci; Angelo Paradiso


Publisher
Springer
Year
2003
Tongue
English
Weight
324 KB
Volume
52
Category
Article
ISSN
0344-5704

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## Abstract Some kinds of breast cancer cell lines, similar to several types of solid tumors, express epidermal growth factor receptor (EGFR). However, gefitinib, an EGFR tyrosine kinase inhibitor, is not effective for all these cell lines. Similarly, taxane is effective for many of the cell lines,