Combined approach of FTIR imaging and conventional dissolution tests applied to drug release
β Scribed by Jaap van der Weerd; Sergei G Kazarian
- Book ID
- 113690620
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 632 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0168-3659
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π SIMILAR VOLUMES
Spectroscopic imaging and a flow-through dissolution test have been combined to improve the possibilities of investigating the release of a poorly soluble drug (diclofenac) from pharmaceutical tablets. The presented methods aim to overcome the limitations that impede the conventional dissolution tes
An automated system for on-line determination of the dissolution rates of drug-delivery formulations to USP Methods I and II is described. The system employs UV-vis spectroscopy utilizing either a fiber-optic probe for direct determination or the option of on-line flow through analysis with prior fi