Combinatorial chemistry of natural produ
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Mikhail F. Gordeev; Gary W. Luehr; Hon C. Hui; Eric M. Gordon; Dinesh V. Patel
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Article
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1998
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Elsevier Science
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French
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An efficient methodology for a solid phase synthesis of D-and L-cycloserine derivatives is described. Fmoc-D-cycloserine 4 and its L-enantiomer 5 prepared by a selective amine acylation of bis-silylated parent compounds are immobilized on Sasrin or 2-chlorotrityl linker resins using Mitsunobu-type r