Combinatorial biosynthesis of polyketides and nonribosomal peptides
โ Scribed by James Staunton; Barrie Wilkinson
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 98 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1367-5931
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Modular polyketide synthases that produce many clinically important natural products such as erythromycins and lovastatins have been engineered in many ways to produce novel natural products. The structural variations have included alterations to the substituents on the macrolide ring, including the
The past year has witnessed a major advance in the study of polyketide and nonribosomal peptide biosynthesis with the identification of the phosphopantetheinyl transferase enzyme family, enzymes required to produce active, post-translationally modified polyketide and peptide synthases. Phosphopantet