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Combinatorial biocatalysis: a natural approach to drug discovery

✍ Scribed by Peter C Michels; Yuri L Khmelnitsky; Jonathan S Dordick; Douglas S Clark

Book ID: 114153049
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 116 KB
Volume: 16
Category: Article
ISSN: 0167-7799
DOI: 10.1016/s0167-7799(98)01190-1

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Scheme 2. Competitive inhibition constants of the library members for the CA-catalyzed hydrolysis of p-nitrophenyl acetate. The non-sulfonamide compounds showed no detectable inhibition at 1 mm.