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Combination of N-acetylcysteine and metformin improves histological steatosis and fibrosis in patients with non-alcoholic steatohepatitis

✍ Scribed by Claudia Pinto Marques Souza De Oliveira; José Tadeu Stefano; Erika Rabelo Forte De Siqueira; Leonardo Soares Silva; Daniel Ferraz De Campos Mazo; Vicência Mara Rodrigues Lima; Carlos Kioshi Furuya; Evandro Sobroza Mello; Fabrício G. Souza; Fabíola Rabello; Telma Eugênio Santos; Monize Aydar Nogueira; Stephen H. Caldwell; Venâncio Avancini Ferreira Alves; Flair José Carrilho


Book ID
118087875
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
251 KB
Volume
0
Category
Article
ISSN
1386-6346

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## Summary **Background** : Increased insulin resistance is the major pathogenic mechanism in the development of non‐alcoholic steatohepatitis. **Aim** : To investigate the therapeutic effect of metformin, a well‐known insulin‐sensitizing agent, in the treatment of non‐alcoholic steatohepatitis.