Combination of N-acetylcysteine and metformin improves histological steatosis and fibrosis in patients with non-alcoholic steatohepatitis
✍ Scribed by Claudia Pinto Marques Souza De Oliveira; José Tadeu Stefano; Erika Rabelo Forte De Siqueira; Leonardo Soares Silva; Daniel Ferraz De Campos Mazo; Vicência Mara Rodrigues Lima; Carlos Kioshi Furuya; Evandro Sobroza Mello; Fabrício G. Souza; Fabíola Rabello; Telma Eugênio Santos; Monize Aydar Nogueira; Stephen H. Caldwell; Venâncio Avancini Ferreira Alves; Flair José Carrilho
- Book ID
- 118087875
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 251 KB
- Volume
- 0
- Category
- Article
- ISSN
- 1386-6346
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## Summary **Background** : Increased insulin resistance is the major pathogenic mechanism in the development of non‐alcoholic steatohepatitis. **Aim** : To investigate the therapeutic effect of metformin, a well‐known insulin‐sensitizing agent, in the treatment of non‐alcoholic steatohepatitis.