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Combination chemotherapy of carboplatin and gemcitabine against solid tumors: a phase I trial

✍ Scribed by D. Tassinari; G. Drudi; I. Panzini; G. Pasini; V. Arcangeli; F. Fochessati; L. Gianni; A. M. Mianulli; G. Oliverio; E. Pasquini; S. Sartori; A. Ravaioli

Publisher
Springer
Year
2001
Tongue
English
Weight
36 KB
Volume
6
Category
Article
ISSN
1341-9625

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## Abstract ## BACKGROUND. Bortezomib is the first proteasome inhibitor to show preliminary evidence of activity against solid tumors. Findings from preclinical studies prompted a Phase I trial to determine the maximum tolerated dose (MTD) and dose‐limiting toxicities (DLTs) of bortezomib in combi