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Column swithiching in high-pressure liquid chromatography

โœ Scribed by J.F.K. Huber; R. Van Der Linden; E. Ecker; M. Oreans


Book ID
104145026
Publisher
Elsevier Science
Year
1973
Tongue
English
Weight
731 KB
Volume
83
Category
Article
ISSN
1873-3778

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โœฆ Synopsis


A high-pressure micro multiport switching valve, its performance and application are described. It is shown that the contribution of column switching to the peak width is negligible with this valve. Different modes of operation are demonstrated:

(I) Control of the total elution of the sample, by-passing the column.

(2) Stripping of a part of the sample, using a sectional column system.

(3) Separation of a complex mixture on a given phase system using columns of different phase ratio.


๐Ÿ“œ SIMILAR VOLUMES


Preparative columns in high-speed liquid
โœ D.R. Baker; R.A. Henry Jr.; R.C. Williams; D.R. Hudson; N.A. Parris ๐Ÿ“‚ Article ๐Ÿ“… 1973 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 733 KB

When high-speed liquid chromatography is used to obtain pure material for subsequent investigation, it can correctly be called preparative, regardless of the sample weights employed. In this paper, the requirements for scaling up from a smalldiameter analytical column to larger-diameter preparative