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Preparative columns in high-speed liquid chromatography

✍ Scribed by D.R. Baker; R.A. Henry Jr.; R.C. Williams; D.R. Hudson; N.A. Parris


Publisher
Elsevier Science
Year
1973
Tongue
English
Weight
733 KB
Volume
83
Category
Article
ISSN
1873-3778

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✦ Synopsis


When high-speed liquid chromatography is used to obtain pure material for subsequent investigation, it can correctly be called preparative, regardless of the sample weights employed. In this paper, the requirements for scaling up from a smalldiameter analytical column to larger-diameter preparative columns are presented. An example of the use of high-speed preparative liquid chromatography to isolate and identify the components of a complex mixture is presented. General requirements of sample size for subsequent investigation are discussed.


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