Colorectal Cancer Risk in Monoallelic Carriers of MYH Variants
β Scribed by Emily L. Webb; Mathew F. Rudd; Richard S. Houlston
- Book ID
- 117854907
- Publisher
- American Society of Human Genetics
- Year
- 2006
- Tongue
- English
- Weight
- 108 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0002-9297
- DOI
- 10.1086/507912
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π SIMILAR VOLUMES
## Dear Sir In a recent study published in the International Journal of Cancer, Fleischmann et al. 1 described the results of screening for germline mutations in the human homolog of the E. coli mutY gene (MYH) in a series of 358 individuals affected with early-onset colorectal cancer (CRC), arbit
## Abstract Cancer risks for a person who has inherited a __MUTYH__ mutation from only one parent (monoallelic mutation carrier) are uncertain. Using the Colon Cancer Family Registry and Newfoundland Familial Colon Cancer Registry, we identified 2,179 firstβ and secondβdegree relatives of 144 incid