Conditional deletion of the colony stimu
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Jia Li; Ken Chen; Liyin Zhu; Jeffrey W. Pollard
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Article
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2006
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John Wiley and Sons
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English
⚖ 526 KB
Colony stimulating factor-1 (CSF-1) is the primary regulator of the mononuclear phagocytic lineage acting through its transmembrane tyrosine kinase receptor, CSF-1R, that is the product of the c-fms proto-oncogene. Null mutations in either the ligand or the receptor genes result in a severe osteopet