Collection and normal levels of the amyloid precursor protein in plasma
β Scribed by Scott Whyte; Neil Wilson; Jon Currie; Paul Maruff; Valencia Malone; Ruxsana Shafiq -Antonacci; Peter Tyler; Kathryn L. Derry; John Underwood; Qiao-Xin Li; Konrad Beyreuther; Dr Colin L. Masters
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 392 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Although the role of choline in blood is not well understood, several recent studies have attempted to link blood choline levels with diseases involving central cholinergic dysfunction [ l , 4, 61. It is well known that myasthenia gravis is a disease involving the neuromuscular junction in man, and
## Abstract Accumulation of Ξ²βamyloid protein (AΞ²) occurs in some muscle fibers of patients with inclusion body myopathy and resembles the type of amyloid deposits seen in the affected tissues of patients with Alzheimer's disease and cerebrovascular amyloidosis. Because mutations in exons 16 and 17
Amyloid precursor protein (APP) is known to be widely expressed in neuronal cells, and enriched in the central and peripheral synaptic sites. Although it has been proposed that APP functions in synaptogenesis, no direct evidence has yet been reported. In this study we investigated the involvement of