Collagen arthritis as a relevant model for rheumatoid arthritis. evidence pro and con

✍ Scribed by David E. Trentham

• Publisher: John Wiley and Sons
• Year: 1982
• Tongue: English
• Weight: 673 KB
• Volume: 25
• Category: Article
• ISSN: 0004-3591
• DOI: 10.1002/art.1780250801

✦ Synopsis

The pathogeny of rheumatoid arthritis consists for the most part of a series of guesses and gaps.

Dr. Llewellyn Jones, 1909 (1)

When a polyarthritis is induced in rats (2-30) or certain strains of mice (3 1-33) by intradermal injection of native heterologous or homologous type I1 collagen emulsified in adjuvant oil, the resulting disease is a model with defined huinoral (3