Comparative Study of Colchicine and Trim
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Virginia Castro; Pablo Muriel
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Article
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1996
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John Wiley and Sons
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English
β 777 KB
The aim of this work was to compare the effects of colchicine and trimethylcolchicinic acid (TMCA) on liver damage induced by bile duct ligation (BDL) for 2 months in male Wistar rats. Colchicine was evaluated at a dose of 10 pg rat-' day-', p.0. only, because higher doses produced diarrhoea and dea