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Cognitive predictors of functional decline in vascular dementia

✍ Scribed by Angela L. Jefferson; Deborah Cahn-Weiner; Patricia Boyle; Robert H. Paul; David J. Moser; Norman Gordon; Ronald A. Cohen

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
47 KB
Volume
21
Category
Article
ISSN
0885-6230

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✦ Synopsis

Abstract

Background

This study examined changes in cognitive‐functional relationships in vascular dementia (VaD) over the course of one year.

Methods

Twenty‐four patients with probable VaD were administered the Dementia Rating Scale (DRS). Caregivers completed an informant‐based measure of instrumental (IADL) and basic activities of daily living (BADL). Follow‐up assessment was conducted one‐year post‐baseline.

Results

Logistic regression revealed that changes in the DRS Initiation/Perseveration and DRS Memory subscales were significantly associated with declines in IADLs and BADLs, respectively.

Conclusions

Among patients with VaD, longitudinal changes in IADLs and BADLs are most strongly associated with changes in executive functioning and memory abilities, respectively. Findings suggest that different cognitive functions subserve complex instrumental and rote, habituated basic functional activities, and neuropsychological screening measures are useful in the prediction of such functional changes. Copyright © 2006 John Wiley & Sons, Ltd.

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