✦ LIBER ✦

Scopolamine-induced cognitive impairment as a predictor of cognitive decline in healthy elderly volunteers

✍ Scribed by Dr. Andrew Barker; Roy Jones; Pauline Simpson; Keith Wesnes

Publisher: John Wiley and Sons
Year: 1995
Tongue: English
Weight: 312 KB
Volume: 10
Category: Article
ISSN: 0885-6230
DOI: 10.1002/gps.930101211

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

There are theoretical grounds for believing that scopolamine‐induced cognitive deficit may be predictive of future cognitive decline. In the present study, 22 healthy elderly volunteers were reassessed 3 years after a scopolamine challenge. Although there was little overall change in mean cognitive test scores over time, in two out of 10 tests scopolamine‐induced decrement was related to subsequent decline.

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