## Background: Chronically hospitalized geriatric inpatients with schizophrenia are at particular risk for both tardive dyskinesia (td) and cognitive impairment but have been insufficiently studied in this regard. similarly, the relationship between td and cognitive impairment has not be adequately
Cognitive functions in chronic schizophrenic patients with tardive dyskinesia
β Scribed by Som. D. Soni; David Neill; Brian Sheffield
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 837 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0885-6222
No coin nor oath required. For personal study only.
β¦ Synopsis
Two groups of chronic stable schizophrenics matched on several parameters but differing only with respect to presence or absence of tardive dyskinesia (TD) were compared for cognitive function using the Bexley Maudsley Automated Psychological Screen and the Category Sorting Test. The results showed that although all schizophrenics performed poorly on the psychometric tests in this inventory, there was no difference between the two groups for any of the cognitive functions tested. Stepwise multiple regression analysis performed on patients with TD revealed that age and extrapyramidal symptom (EPS) score were the only variables consistently associated with oro-facial TD where as EPS correlated inversely with TD of limbs and trunk. Our results did not support the hypothesis that tardive dyskinesia in schizophrenic patients is associated with additional or specific cognitive dysfunction. KEY worm-Chronic schizophrenia, tardive dyskinesia, cognitive dysfunction.
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Relationships between tardive dyskinesia (TD) and the life expectancy of schizophrenic patients who suffer it were examined in two studies over a 50-month period. In a prospective study, the mortality rate was found to be higher in patients with T D than in those without. This suggests either that T
The present study was undertaken to investigate the relationship between tardive dyskinesia (TD) and polydipsia. The Abnormal Involuntary Movement Scale (AIMS) and percent of maximum weight gain (PMWG)/week were simultaneously examined in 163 hospitalized patients receiving neuroleptic treatment. Pa
## Abstract Tardive dyskinesia (TD) occurs in approximately 20% of patients exposed to longβterm antipsychotic treatment and may be influenced by genetic predisposition, in addition to clinical risk factors. In this study, we implemented a twoβstep approach to identify susceptibility genes for TD.
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