## Abstract Valproate embryopathy is a well recognized syndrome caused by prenatal exposure to the anticonvulsant valproic acid (Depakote). We report five halfβsiblings with the same mother (four different fathers) who all have valproate embryopathy. Valproic acid was the sole anticonvulsant in all
Cognitive effects of valproate
β Scribed by Roberto Gallassi; Angela Morreale; Sebastiano Lorusso; Gaetano Procaccianti; Elio Lugaresi; Agostino Baruzzi
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 341 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0920-1211
No coin nor oath required. For personal study only.
β¦ Synopsis
The effects of valproate on cognition are usually considered to be minimal, but few formal neuropsychological studies are available. We studied the psychomotor performances of 20 seizure-free epileptics during fixed valproate monotherapy and after its withdrawal. Our findings suggest some adverse effects of valproate which appear to be completely reversible after withdrawal.
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