Protein labeling by reductive methylatio
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Neil Jentoft; Dorr G. Dearborn
📂
Article
📅
1980
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Elsevier Science
🌐
English
⚖ 415 KB
have demonstrated that reductive methylation with labeled formaldehyde and NaCNBH, provides a simple method for specifically labeling the amino groups of proteins using extremely mild reaction conditions. However, cyanide, which is one of the products of the reaction, reduces labeling efficiency by