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Coexpression Pattern of C-MYC Associated Genes in a Small Cell Lung Cancer Cell Line with High Steady State C-MYC Transcription

✍ Scribed by S. Dooley; I. Wundrack; N. Blin; C. Welter


Book ID
115577122
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
474 KB
Volume
213
Category
Article
ISSN
0006-291X

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## Small -cell-lung-cancer (SCLC) is characterized by rapid development of resistance to cytotoxic agents, such as cisplatin (cDDP) and anthracyclines. c-myc over-expression is one of the reported genetic alterations in this tumor. Amplification of the c-myc gene in this and other cancers is often