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Gene amplification and P1/P2 promoter shift as mechanisms of c-myc transcriptional activation in small cell lung cancer

โœ Scribed by Steven Dooley; Iris Wundrack; Cornelius Welter; Klaus-Dieter Zang; Nikolaus Blin


Book ID
119106244
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
101 KB
Volume
77
Category
Article
ISSN
0165-4608

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## Abstract The Runx2 factor is an essential component of the regulatory mechanisms that control transcription during skeletogenesis. Runx2/p57 expression in osteoblastic cells is controlled by the P1 promoter, which is recognized by key regulators of osteoblast differentiation including homeodomai