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Codon bias and heterologous protein expression

โœ Scribed by Claes Gustafsson; Sridhar Govindarajan; Jeremy Minshull


Book ID
111863463
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
182 KB
Volume
22
Category
Article
ISSN
0167-7799

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โœ Charles Kurland; Jonathan Gallant ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 419 KB

Missense substitutions and processivity errors in the translation of heterologous proteins are expected to occur at higher frequencies than the corresponding errors of normal translation. The resulting error-containing products may overload chaperone systems. Likewise, there may be a risk of an immu