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Cocaine increases 5-HT1B mRNA in rat nucleus accumbens shell neurons

✍ Scribed by B.J. Hoplight; E.S. Vincow; J.F. Neumaier

Book ID
116784698
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
279 KB
Volume
52
Category
Article
ISSN
0028-3908

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Cocaine induces an increase in hippocampal and nucleus accumbens (Nac) serotonin (5-HT) concentration parallel to locomotor activation. Both effects can be modulated by systemic 5-HT 1A -receptor agonism/antagonism. Given the contribution of the hippocampus to spontaneous behavioral activity, these