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Cobalt-catalyzed alkenylation of organomagnesium reagents

✍ Scribed by Gérard Cahiez; Hovsep Avedissian

Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
221 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis

Alkenyl iodides, bromides and chlorides react with organomagnesium reagents in THF, in the presence of Co(acac)2 and NMP (9 to 4 equiv.), to give the cross-coupling products in good yields. The reaction is chemoselective (aryl or alkyl bromides, esters and ketones) and stereoselective (> 99.5%).

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