Coamplification of the L-mycand N-mycOncogenes in a Neuroblastoma Cell Line
โ Scribed by Jinbo, Takeshi ;Iwamura, Yukio ;Kaneko, Michio ;Sawaguchi, Shigenori
- Book ID
- 108578951
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1989
- Tongue
- English
- Weight
- 167 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0910-5050
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We characterized differences in the structural organization of the MYCN amplicons of a number of neuroblastomas by analyzing 8 contigs spanning 330 kb cloned from the MYCN amplicon of a neuroblastoma cell line. Some regions were amplified in almost all specimens, the conserved regions (CRs), and oth
Whilst many human neuroblastorna cell lines have been studied to see if they are capable of taking up mlBG, few appear to have this ability. This contrasts markedly to the situation in vivo, where uptake has been demonstrated in the majority of tumours investigated. Here we report on the human neuro