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Coagulation Disorders and Bleeding in Liver Disease: Future Directions

✍ Scribed by Caldwell, Stephen H.; Sanyal, Arun J.


Book ID
123097058
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
58 KB
Volume
13
Category
Article
ISSN
1089-3261

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Normal coagulation has classically been conceptualized as a Y-shaped pathway, with distinct "intrinsic" and "extrinsic" components initiated by factor XII or factor VIIa/ tissue factor, respectively, and converging in a "common" pathway at the level of the FXa/FVa (prothrombinase) complex. Until rec