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Clustering of protein kinase A-dependent CFTR chloride channels in the sarcolemma of guinea-pig ventricular myocytes

✍ Scribed by Andrew F. James; Razshan Z. Sabirov; Yasunobu Okada

Book ID
116299553
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
315 KB
Volume
391
Category
Article
ISSN
0006-291X

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We investigated the effects of the purified catalytic subunit (C subunit) of the cAMP-dependent protein kinase (A-kinase) on the cardiac Na+ channel currents. Single Na+ channel currents in guinea-pig ventricular myocytes were recorded using the patch clamp technique of the inside-out configuration.