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Clusterin induces matrix metalloproteinase-9 expression via ERK1/2 and PI3K/Akt/NF- B pathways in monocytes/macrophages

✍ Scribed by Shim, Y.-J.; Kang, B.-H.; Jeon, H.-S.; Park, I.-S.; Lee, K.-U.; Lee, I.-K.; Park, G.-H.; Lee, K.-M.; Schedin, P.; Min, B.-H.

Book ID: 120655452
Publisher: Society for Leukocyte Biology
Year: 2011
Tongue: English
Weight: 624 KB
Volume: 90
Category: Article
ISSN: 0741-5400
DOI: 10.1189/jlb.0311110

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## Abstract The expression of matrix metalloproteinase‐9 (MMP‐9) has been implicated in progression of atherosclerotic lesions. The role and importance of the signaling pathway in the transcriptional regulation of MMP‐9 in human aortic smooth muscle cells (HASMC) was examined. Tumor necrosis factor