This report investigates the possibility that the ganglioside GM2 is a common target structure for natural killer cells. A subpop-ulation of lymphocytes, NK cells may play a role in vivo in controlling the growth of certain tumors.
Clustered carbohydrates as a target for natural killer cells: a model system
β Scribed by Elena I. Kovalenko; Elena Abakushina; William Telford; Veena Kapoor; Elena Korchagina; Sergei Khaidukov; Irina Molotkovskaya; Alexander Sapozhnikov; Pavel Vlaskin; Nicolai Bovin
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 659 KB
- Volume
- 127
- Category
- Article
- ISSN
- 1432-119X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The mechanism of recognition by natural killer (NK) cells is still unknown. A dynamic model is formulated describing recognition of NK-sensitive target cells (TCs) by NK cells or NK-like cells. This model does not assume the presence of the specific NK-receptor(s) on the membrane of NK cells and cor
Although human N K cells lyse a wide spectrum of target cells, the precise target structure recognized by N K cells has not yet been elucidated. In order to define a possible relationship between gangliosides on human target cells and susceptibility to N K lysis. 14 human leukemia and lymphoma cell
Pegylated polystyrene particles (PS-PEG) were prepared as a model system for artificial cells, by modification of carboxyl polystyrene particles (PS-COOH) with homo- and hetero-bifunctional polyethylene glycols (PEG, MW 1500, 3400, and 5000) containing an amino end group for immobilization and an am