Clostridium Difficile. Its Role in Intestinal Disease

✍ Scribed by Rial D. Rolfe (Eds.)

• Publisher: Academic Press
• Year: 1988
• Tongue: English
• Leaves: 393
• Category: Library

✦ Synopsis

Despite the tremendous progress made during the last few years in understanding the pathogenesis, epidemiology, diagnosis, and treatment of Clostridium difficile-associated intestinal disease, many extremely important and fundamental questions remain to be answered. The objectives of this book are to summarize the available information regarding Clostridium difficile and its role in intestinal disease and to serve as a basis for future investigations in this challenging area.
Clostridium difficile: its role in Intestinal Disease. An excellent volume that should appeal not only to the devotee of C difficile but to all gastroenterologists and microbiologists, this will not languish on my library shelves like so many other books I have reviewed. It will be regularly thumbed. --R.H. George, consultant microbiologist, Children's Hospital, Birmingham
Clostridium difficile: Its Role in Intestinal disease. The book is well written and informative; it has a vast amount of information packed in it...this book would be a welcome addition to the researchers and clinicians interested in C difficile-associated intestinal diseases. --Edward Balish, University of Wisconsin Medical School

✦ Table of Contents

Content:
Front Matter, Page iii
Copyright, Page iv
Contributors, Pages xiii-xiv
Preface, Pages xv-xvi, Rial D. Rolfe, Sydney M. Finegold
Chapter 1 - Introduction, Pages 1-13, JOHN BARTLETT
Chapter 2 - Historical Aspects, Pages 15-28, A. TREVOR WILLIS
Chapter 3 - Antimicrobial Agent–Associated Diarrhea in Adult Humans, Pages 31-44, W. LANCE GEORGE
Chapter 4 - Clostridium difficile in Infants and Children, Pages 45-64, MICHAEL COOPERSTOCK
Chapter 5 - Other Clostridial Causes of Diarrhea and Colitis in Man and Animals, Pages 65-98, S.P. BORRIELLO, R.J. CARMAN
Chapter 6 - Immunological Response to Clostridium difficile Infection, Pages 99-112, BO ARONSSON, MARTA GRANSTRÖM
Chapter 7 - Role of the Hamster Model of Antibiotic-Associated Colitis in Defining the Etiology of the Disease, Pages 115-125, ANDREW B. ONDERDONK
Chapter 8 - Other Animal Models of Intestinal Disease Caused by Clostridia, Pages 127-141, ROBERT FEKETY
Chapter 9 - Purification and Properties of Toxins A and B of Clostridium difficile, Pages 145-167, DAVID M. LYERLY, TRACY D. WILKINS
Chapter 10 - Mechanism of Action of Clostridium difficile Toxins, Pages 169-181, SAM T. DONTA
Chapter 11 - Microbial Ecology of Clostridium difficile, Pages 183-200, KENNETH H. WILSON
Chapter 12 - Asymptomatic Intestinal Colonization by Clostridium difficile, Pages 201-225, RIAL D. ROLFE
Chapter 13 - General Epidemiology, Potential Reservoirs, and Typing Procedures, Pages 229-256, MAURY E. MULLIGAN
Chapter 14 - Pathology and Diagnosis of Clostridium difficile Disease, Pages 259-270,CP1,CP2,271-286, DALE N. GERDING, LANCE R. PETERSON, ROGER L. GEBHARD, HATTON W. SUMNER
Chapter 15 - Isolation and Identification of Clostridium difficile; Tissue Culture Cytotoxicity Assay, Pages 287-307, MARTHA A.C. EDELSTEIN
Chapter 16 - Other Potential Diagnostic Techniques, Pages 309-338, HANNAH WEXLER
Chapter 17 - Therapy Directed against Clostridium difficile and Its Toxins: Complications of Therapy, Pages 341-357, SYDNEY M. FINEGOLD, W. LANCE GEORGE
Chapter 18 - Surgical Aspects of Therapy, Pages 359-366, IRA P. MARKOWITZ, RONALD LEE NICHOLS
Chapter 19 - Prevention of Clostridium difficile–Associated Intestinal Disease, Pages 367-379, JOSEPH SILVA JR.
Chapter 20 - Conclusions and Unanswered Questions, Pages 383-390, RIAL D. ROLFE, SYDNEY M. FINEGOLD
Index, Pages 391-408