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Cloning, sequencing, and biochemical characterization of the nostocyclopeptide biosynthetic gene cluster: molecular basis for imine macrocyclization

โœ Scribed by Julia E. Becker; Richard E. Moore; Bradley S. Moore


Book ID
116506561
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
307 KB
Volume
325
Category
Article
ISSN
0378-1119

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The cephabacins, one of the b-lactam antibiotics, are produced by Lysobacter lactamgenus. The previous studies the cephabacin biosynthesis were limited to a gene cluster that encodes the gene products responsible for the biosynthesis of the cephem nucleus. The long-term goal of this research is to e