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Cloning of the Rat Tissue Inhibitor of Metalloproteinases Type 2 (TIMP-2) Gene: Analysis of Its Expression in Normal and Transformed Thyroid Cells

✍ Scribed by Massimo Santoro; Caterina Battaglia; Li Zhang; Francesca Carlomagno; Maria Luisa Martelli; Domenico Salvatore; Alfredo Fusco


Book ID
115601800
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
408 KB
Volume
213
Category
Article
ISSN
0014-4827

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Rous sarcoma virus-transformed chicken embryo fibroblasts (RSVCEF), when compared to normal CEF, produce elevated levels of matrix metalloproteinase-2 (MMP-2) that exists in a form free of complexed tissue inhibitor of metalloproteinase-2 (TIMP-2). In order to ascertain whether the increased levels