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Cloning of the mouse 25-hydroxyvitamin D3-1α-hydroxylase (CYP1α) gene

✍ Scribed by Christine Kimmel-Jehan; Hector F. DeLuca

Book ID: 117480649
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 581 KB
Volume: 1475
Category: Article
ISSN: 0304-4165
DOI: 10.1016/s0304-4165(00)00065-9

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## Abstract Mutations in the human 25‐hydroxyvitamin‐D~3~‐1α‐hydroxylase (CYP27B1) gene cause pseudo vitamin D deficiency rickets (PDDR). The kidney is the main site of expression of the __CYP27B1__ gene, but expression has been documented in other cell types, including chondrocytes. We engineered