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Cloning of the low-affinity murine granulocyte-macrophage colony stimulating factor receptor and reconstitution of a high-affinity receptor complex

โœ Scribed by Manaster, B.J.; Mann, Ronald J.; Rubenstein, Scott


Book ID
122560623
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
166 KB
Volume
3
Category
Article
ISSN
1043-4666

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Radioiodinated granulocyte-macrophage colony-stimulating factor (1251-GM-CSF) binds to specific receptors (molecular weight approximately 50,000 daltons) on the murine myelomonocytic leukemia, WEHI-3BD+. At 4OC 1251-CM-CSF remains on the surface of the cells and can be eluted by washing the cells wi