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Cloning and sequencing of the cDNAs encoding two alternative splicing-derived variants of the alpha subunit of the granulocyte-macrophage colony-stimulating factor receptor

โœ Scribed by Xiaotang Hu; Peter D. Emanuel; Kenneth S. Zuckerman

Book ID
116106190
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
251 KB
Volume
1223
Category
Article
ISSN
0167-4889

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Cloning and sequencing of an alternative
Cloning and sequencing of an alternative splicing-derived cDNA variant of the GM-CSF receptor alpha subunit, which encodes a truncated protein
โœ Hu, Xiaotang; Zuckerman, Kenneth S. ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 79 KB ๐Ÿ‘ 1 views

GM-CSF interacts with the low affinity GM-CSF receptor โฃ-subunit, which leads to high affinity association with the โฃ-subunit/common โค-subunit complex and transduction of intracellular signals leading to proliferation, differentiation, and/or activation of hemopoietic cells, predominantly in the neu