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Cloning of the Human Tissue Inhibitor of Metalloproteinase-4 Gene (TIMP4) and Localization of the TIMP4 andTimp4Genes to Human Chromosome 3p25 and Mouse Chromosome 6, Respectively

✍ Scribed by Timothy M. Olson; Satoshi Hirohata; Jean Ye; Kevin Leco; Michael F. Seldin; Suneel S. Apte


Book ID
115614365
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
136 KB
Volume
51
Category
Article
ISSN
0888-7543

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Localization of the CDKN4/p27Kip1gene to
✍ Emmanuel Martin; ValΓ¨re Cacheux; HΓ©lΓ¨ne CavΓ©; Jean Michel Lapierre; Denis Paslie πŸ“‚ Article πŸ“… 1995 πŸ› Springer 🌐 English βš– 774 KB

CDKN4/p27Kip1 is a cyclin-dependent kinase (Cdk) inhibitor implicated in G1 phase arrest, which negatively regulates G1 phase progression in response to TGF beta, and might represent a tumor suppressor gene. We report here the chromosomal assignment of the human CDKN4 gene to chromosome 12p12.3 in c