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Cloning of the Chromosome Translocation Breakpoint Junction of the t(14;19) in Chronic Lymphocytic Leukemia

โœ Scribed by Timothy W. McKeithan, Janet D. Rowley, Thomas B. Shows and Manuel O. Diaz

Book ID
123635052
Publisher
National Academy of Sciences
Year
1987
Tongue
English
Weight
800 KB
Volume
84
Category
Article
ISSN
0027-8424

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Identification of a transcriptional unit
Identification of a transcriptional unit adjacent to the breakpoint in the 14;19 translocation of chronic lymphocytic leukemia
โœ Timothy W. McKeithan; Hitoshi Ohno; Manuel O. Diaz ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 829 KB

The t( 14; 19)(q32.3;q I 3. I ) is a recurring translocation found in the neoplastic cells of some patients with chronic lymphocytic leukemia (CLL). W e have previously cloned the translocation breakpoint junction present in the leukemic cells from one such patient. In the present study, we have clo