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Cloning of the 5’Upstream Region of theRat p16Gene and Its Role in Silencing

✍ Scribed by Abe, Masanobu ;Okochi, Eriko ;Kuramoto, Takashi ;Kaneda, Atsushi ;Takato, Tsuyoshi ;Sugimura, Takashi ;Ushijima, Toshikazu

Book ID
108582093
Publisher
Wiley (Blackwell Publishing)
Year
2002
Tongue
English
Weight
338 KB
Volume
93
Category
Article
ISSN
0910-5050

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## Abstract We isolated the __p53__ gene from Syrian hamster embryo cells by cosmid cloning procedures. The organization of the hamster __p53__ gene was similar to that of other mammalian __p53__ genes; it had 11 exons, a noncoding exon 1, and a long intron 1 (about 6.5 kb). The upstream __p53__ pr