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Cloning of E6 and E7 Genes of Human Papilloma Virus Type 18 and Transformation Potential of E7 Gene and its Mutants

✍ Scribed by Majid Laassri; Larissa Gul'ko; Svetlana Vinokurova; Natalia Kisseljova; Vladimir Veiko; Fjodor Kisseljov

Book ID
110257552
Publisher
Springer
Year
1999
Tongue
English
Weight
202 KB
Volume
18
Category
Article
ISSN
0920-8569

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✍ Olga Medina-MartΓ­nez; VerΓ³nica Vallejo; Miriam C. Guido; Alejandro GarcΓ­a-Carran πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 116 KB πŸ‘ 1 views

Human papillomavirus (HPV) DNA sequences are found in most carcinomas originating from the uterine cervix. HPV E6 and E7 oncogenes have been shown to cooperate with ras oncogenes to fully transform human epithelial cells. We investigated the effect of the Ha-ras oncogene on the transcriptional activ