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Cloning, expression, isolation, and properties of thymidine kinase from herpes simplex virus type 1, strain L2

✍ Scribed by V. N. Stepanenko; R. S. Esipov; A. I. Miroshnikov; V. L. Andronova; G. A. Galegov; M. V. Yasko; A. A. Gus’kova; A. Yu. Skoblov; Yu. S. Skoblov

Book ID
111457216
Publisher
SP MAIK Nauka/Interperiodica
Year
2011
Tongue
English
Weight
399 KB
Volume
37
Category
Article
ISSN
1068-1620

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✍ Kudo, E.; Shiota, H.; Naito, T.; Satake, K.; Itakura, M. 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 416 KB 👁 2 views

Drug-resistance of herpes simplex virus (HSV) is caused most frequently by mutation of the viral thymidine kinase (TK) gene. To elucidate the significance of detecting nucleotide changes of the TK gene for screening drug-resistant viruses, the frequency and variation of the genetic polymorphisms in