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Cloning and sequencing of cDNAs encoding the full-length mouse mannose 6-phosphate/insulin-like growth factor II receptor

✍ Scribed by Ludwig, Thomas; Tenscher, Kirsten; Remmler, Jill; Hoflack, Bernard; Lobel, Peter


Book ID
123434895
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
417 KB
Volume
142
Category
Article
ISSN
0378-1119

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The ability of acute insulin treatment to elicit a redistribution of the liver insulin-like growth factor-II/ mannose 6-phosphate (IGF-II/M6P) receptor has been studied in rats, using cell fractionation. Injection of insulin (0.4 -50 g) led to a time-and dose-dependent decrease in IGF-II binding act